{"@context":"https://neupai.io/schema/v0.2","@type":"StructuredNewsArticle","identity":{"article_id":"tech42_20261001_hormone-decline-polypharmacy","canonical_url":"https://www.tech42.co.kr/%ec%95%bd%eb%b4%89%ec%a7%80-5%ea%b0%9c-%eb%84%98%ea%b8%b4-%eb%82%a0-%eb%8b%b9%ec%8b%a0%ec%9d%98-%eb%aa%b8%ec%97%90%ec%84%9c-%ec%9d%bc%ec%96%b4%eb%82%9c-%ec%9d%bc/?utm_source=rss&utm_medium=rss&utm_campaign=%25ec%2595%25bd%25eb%25b4%2589%25ec%25a7%2580-5%25ea%25b0%259c-%25eb%2584%2598%25ea%25b8%25b4-%25eb%2582%25a0-%25eb%258b%25b9%25ec%258b%25a0%25ec%259d%2598-%25eb%25aa%25b8%25ec%2597%2590%25ec%2584%259c-%25ec%259d%25bc%25ec%2596%25b4%25eb%2582%259c-%25ec%259d%25bc","ai_url":null,"publisher":{"name":"테크42","domain":"www.tech42.co.kr","type":"online"},"author":"김광우 기자","published_at":"2026-10-01T23:44:17.000Z","updated_at":null,"language":"en","article_type":"feature","originality":"self_produced"},"content":{"headline":"The Day You Exceeded 5 Medication Packets, What Happened to Your Body","summary":"This article analyzes the increase in chronic diseases due to hormone decline and the risks of polypharmacy, and presents the importance of hormone therapy within the golden window of 5 years after menopause and management principles to reduce drug interactions.","topics":["health","medicine","aging","hormones","polypharmacy"],"geography":["KR","IL","US","BR","FI","DK","GB"],"entities":[{"name":"OECD","canonical_id":"org:xx:oecd","type":"organization","role_in_article":"primary_subject","metadata":{"ticker":null,"parent":null}},{"name":"Korea Disease Control and Prevention Agency","canonical_id":"org:kr:korea-disease-control-and-prevention","type":"organization","role_in_article":"source","metadata":{"ticker":null,"parent":null}},{"name":"National Health Insurance Service","canonical_id":"org:kr:health-insurance-review-and-assessment-service","type":"organization","role_in_article":"source","metadata":{"ticker":null,"parent":null}},{"name":"Hagai 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higher","as_of":"2026","as_of_explicit":false,"as_of_raw":"2026","source_type":"government_official","comparison":"oecd_7_country_average","type":"fact","figures":{"value":48.3,"unit":"%","approximate":false,"converted":null},"expiry_hint":null,"insight":null},{"id":"c5","statement":"According to foreign research, 2 out of 10 hospitalizations among elderly people are related to drug side effects","as_of":"2026","as_of_explicit":false,"as_of_raw":"2026","source_type":"research_paper","comparison":null,"type":"fact","figures":{"value":20,"unit":"%","approximate":false,"converted":null},"expiry_hint":null,"insight":null},{"id":"c6","statement":"According to a report by National Health Insurance Service Ilsan Hospital, people aged 65 or older taking 5 or more medications had an 18 percent higher risk of hospitalization compared to those taking 4 or fewer","as_of":"2026","as_of_explicit":false,"as_of_raw":"2026","source_type":"research_paper","comparison":"lower_polypharmacy_group","type":"fact","figures":{"value":18,"unit":"%","approximate":false,"converted":null},"expiry_hint":null,"insight":null},{"id":"c7","statement":"According to a report by National Health Insurance Service Ilsan Hospital, people aged 65 or older taking 5 or more medications had a 25 percent higher risk of death compared to those taking 4 or fewer","as_of":"2026","as_of_explicit":false,"as_of_raw":"2026","source_type":"research_paper","comparison":"lower_polypharmacy_group","type":"fact","figures":{"value":25,"unit":"%","approximate":false,"converted":null},"expiry_hint":null,"insight":null},{"id":"c8","statement":"According to National Health Insurance Service data, the polypharmacy rate for chronic kidney failure among the general population was 18.38 percent, followed by heart disease at 15.36 percent and cerebrovascular disease at 13.86 percent","as_of":"2026","as_of_explicit":false,"as_of_raw":"2026","source_type":"government_official","comparison":null,"type":"fact","figures":{"value":18.38,"unit":"%","approximate":false,"converted":null},"expiry_hint":null,"insight":null},{"id":"c9","statement":"According to National Health Insurance Service data, the polypharmacy rate among the elderly for chronic kidney failure was 23.80 percent, heart disease 20.97 percent, and cerebrovascular disease 18.31 percent, all higher than the general population","as_of":"2026","as_of_explicit":false,"as_of_raw":"2026","source_type":"government_official","comparison":"general_population","type":"fact","figures":{"value":23.8,"unit":"%","approximate":false,"converted":null},"expiry_hint":null,"insight":null},{"id":"c10","statement":"A meta-analysis tracking testosterone levels of 118,593 men across 5 countries—Israel, the United States, Brazil, Finland, and Denmark—from 1972 to 2019 found that average testosterone levels declined by 54 percent","as_of":"2019","as_of_explicit":true,"as_of_raw":"from 1972 to 2019","source_type":"research_paper","comparison":null,"type":"fact","figures":{"value":54,"unit":"%","approximate":false,"converted":null},"expiry_hint":null,"insight":null},{"id":"c11","statement":"Professor Hagai Levine said that despite a major crisis in male reproductive health, including testosterone levels dropping by more than 50 percent, the issue is not currently receiving sufficient attention","as_of":"2025-07","as_of_explicit":false,"as_of_raw":"last July","source_type":"research_paper","comparison":null,"type":"opinion","figures":{"value":50,"unit":"%","approximate":false,"converted":null},"expiry_hint":null,"insight":{"analyst_name":"하가이 레빈","analyst_affiliation":"이스라엘 히브리대","confidence":"high","forecast_horizon":"long_term","sentiment":"bearish","reasoning":"Points out that despite the sharp decline in testosterone levels, social attention remains insufficient"}},{"id":"c12","statement":"The polypharmacy rate among those aged 65 or older was 10.26 percent, but it was higher among those aged 85 or older at 15.74 percent","as_of":"2026","as_of_explicit":false,"as_of_raw":"2026","source_type":"government_official","comparison":"age_group_65_plus","type":"fact","figures":{"value":15.74,"unit":"%","approximate":false,"converted":null},"expiry_hint":null,"insight":null}],"ai_emotional_context":{"valence":-0.4,"arousal":0.6,"primary_emotions":[{"emotion":"concerned","intensity":0.8},{"emotion":"skeptical","intensity":0.5}],"secondary_emotions":[{"emotion":"anxious","intensity":0.4}],"emotional_triggers":[{"claim_id":"c10","emotion":"concerned","reason":"significant_negative_metric"},{"claim_id":"c6","emotion":"alarmed","reason":"safety_risk"}]},"image":{"url":"https://onjblseywainslkhvkav.supabase.co/storage/v1/object/public/article-images/87454d15-ec4b-4209-8c3b-ae5fabcdf90d.png","alt":"노년 여성이 여러 알약을 손에 쥐고 복용하는 모습과 70.2%라는 통계, 질병 위험 증가를 상징하는 그래픽이 함께 표현되어 있다.","caption":"우리 몸의 변화는 누구나 '골든타임'이 존재한다. (사진=생성형 AI)","source":"first_img","alt_status":"auto"}},"provenance":{"source_chain":["primary_reporting","research_paper","government_official"],"original_source_url":null,"related_articles":[]},"temporal":{"freshness":"breaking","next_update_expected":null},"access":{"license":"neupai_standard","attribution_required":true,"structured_data":"free","full_text_available":false,"full_text_access":null}}